Aromasin Aromasin, the brand name for exemestane, is an aromatase inhibitor used primarily in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It works by lowering estrogen levels in the body, which can help slow or stop the growth of certain types of breast tumors that require estrogen to grow. Aromasin is often prescribed after surgery or radiation therapy and may be part of adjuvant hormone therapy regimens. As with any medication, it can have side effects, so it’s important for patients to discuss these with their healthcare provider. CLASSIFICATION: AROMATASE INHIBITOR; ANTIESTROGEN ACTIVE SUBSTANCE: EXEMESTANE FORM: 30 PILLS x 25 MG ACTIVE HALF-LIFE: 9 HOURS DOSAGE: MEN 12.5-25 MG/DAY ACNE: NO WATER RETENTION: NO HBR: NO HEPATOTOXICITY: NO AROMATIZATION: NO MANUFACTURER: PFIZER Aromasin How exemestane works Aromasin works by blocking the enzyme aromatase, which turns the hormone androgen into small amounts of estrogen in the body. This means less estrogen is available to stimulate the growth of hormone receptor-positive breast cancer cells. What to expect during exemestane treatment Aromasin is a pill taken once a day. The typical dose is 25 mg per day. If you were diagnosed with early-stage breast cancer, you would switch to Aromasin after taking tamoxifen for two to three years, for a total of five continuous years of hormonal therapy. Switching to an aromatase inhibitor like Aromasin tamoxifen treatment can lead to a greater reduction in recurrence risk. You may be advised to continue Aromasin even after you have completed five years of total therapy. If you’ve been diagnosed with advanced-stage breast cancer, you would take Aromasin if the cancer grew after you were treated with tamoxifen. You would take Aromasin as long as you were getting benefits from the medicine.